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Ultrasensitivity and bistability in covalent-modification cycles with positive autoregulation

Switch-like behaviours in biochemical networks are of fundamental significance in biological signal processing, and exist as two distinct types: ultra-sensitivity and bistability. Here we propose two new models of a reversible covalent-modification cycle with positive autoregulation (PAR), a motif s...

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Detalles Bibliográficos
Autores principales: Jeynes-Smith, Cailan, Araujo, Robyn P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331239/
https://www.ncbi.nlm.nih.gov/pubmed/35153570
http://dx.doi.org/10.1098/rspa.2021.0069