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Ultrasensitivity and bistability in covalent-modification cycles with positive autoregulation
Switch-like behaviours in biochemical networks are of fundamental significance in biological signal processing, and exist as two distinct types: ultra-sensitivity and bistability. Here we propose two new models of a reversible covalent-modification cycle with positive autoregulation (PAR), a motif s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331239/ https://www.ncbi.nlm.nih.gov/pubmed/35153570 http://dx.doi.org/10.1098/rspa.2021.0069 |