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Effect of Enzyme-Inducing Antiseizure Medications on the Risk of Sub-Therapeutic Concentrations of Direct Oral Anticoagulants: A Retrospective Cohort Study

BACKGROUND: Stroke and thromboembolic events occurring among patients taking direct oral anticoagulants (DOACs) have been associated with low concentrations of DOACs. Enzyme-inducing antiseizure medications (EI-ASMs) are associated with enhanced cytochrome-P450-mediated metabolism and enhanced P-gly...

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Detalles Bibliográficos
Autores principales: Perlman, Amichai, Goldstein, Rachel, Choshen Cohen, Lotan, Hirsh-Raccah, Bruria, Hakimian, David, Matok, Ilan, Kalish, Yosef, Singer, Daniel E., Muszkat, Mordechai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332574/
https://www.ncbi.nlm.nih.gov/pubmed/33595834
http://dx.doi.org/10.1007/s40263-021-00795-z