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Effect of Enzyme-Inducing Antiseizure Medications on the Risk of Sub-Therapeutic Concentrations of Direct Oral Anticoagulants: A Retrospective Cohort Study

BACKGROUND: Stroke and thromboembolic events occurring among patients taking direct oral anticoagulants (DOACs) have been associated with low concentrations of DOACs. Enzyme-inducing antiseizure medications (EI-ASMs) are associated with enhanced cytochrome-P450-mediated metabolism and enhanced P-gly...

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Detalles Bibliográficos
Autores principales:	Perlman, Amichai, Goldstein, Rachel, Choshen Cohen, Lotan, Hirsh-Raccah, Bruria, Hakimian, David, Matok, Ilan, Kalish, Yosef, Singer, Daniel E., Muszkat, Mordechai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332574/ https://www.ncbi.nlm.nih.gov/pubmed/33595834 http://dx.doi.org/10.1007/s40263-021-00795-z

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