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Regulatory mechanisms of ryanodine receptor/Ca(2+) release channel revealed by recent advancements in structural studies
Ryanodine receptors (RyRs) are huge homotetrameric Ca(2+) release channels localized to the sarcoplasmic reticulum. RyRs are responsible for the release of Ca(2+) from the SR during excitation–contraction coupling in striated muscle cells. Recent revolutionary advancements in cryo-electron microscop...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332584/ https://www.ncbi.nlm.nih.gov/pubmed/32040690 http://dx.doi.org/10.1007/s10974-020-09575-6 |