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Regulatory mechanisms of ryanodine receptor/Ca(2+) release channel revealed by recent advancements in structural studies

Ryanodine receptors (RyRs) are huge homotetrameric Ca(2+) release channels localized to the sarcoplasmic reticulum. RyRs are responsible for the release of Ca(2+) from the SR during excitation–contraction coupling in striated muscle cells. Recent revolutionary advancements in cryo-electron microscop...

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Detalles Bibliográficos
Autores principales: Ogawa, Haruo, Kurebayashi, Nagomi, Yamazawa, Toshiko, Murayama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332584/
https://www.ncbi.nlm.nih.gov/pubmed/32040690
http://dx.doi.org/10.1007/s10974-020-09575-6