Effect of Varying Degrees of Renal Impairment on the Pharmacokinetics of Omecamtiv Mecarbil

BACKGROUND AND OBJECTIVE: Omecamtiv mecarbil is a novel selective cardiac myosin activator (myotrope) under investigation for the treatment of heart failure with reduced ejection fraction. The objective of this clinical study was to estimate the effect of varying degrees of renal impairment on the p...

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Detalles Bibliográficos
Autores principales: Trivedi, Ashit, Oberoi, Rajneet K., Jafarinasabian, Pegah, Zhang, Hanze, Flach, Stephen, Abbasi, Siddique, Dutta, Sandeep, Lee, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332597/
https://www.ncbi.nlm.nih.gov/pubmed/33768487
http://dx.doi.org/10.1007/s40262-021-01014-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332597/
https://www.ncbi.nlm.nih.gov/pubmed/33768487
http://dx.doi.org/10.1007/s40262-021-01014-0

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