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Contribution of the Gut Microbiome to Drug Disposition, Pharmacokinetic and Pharmacodynamic Variability

The trillions of microbes that make up the gut microbiome are an important contributor to health and disease. With respect to xenobiotics, particularly orally administered compounds, the gut microbiome interacts directly with drugs to break them down into metabolic products. In addition, microbial p...

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Detalles Bibliográficos
Autores principales: Tsunoda, Shirley M., Gonzales, Christopher, Jarmusch, Alan K., Momper, Jeremiah D., Ma, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332605/
https://www.ncbi.nlm.nih.gov/pubmed/33959897
http://dx.doi.org/10.1007/s40262-021-01032-y