Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds

Spontaneous canine cancers are valuable but relatively understudied and underutilized models. To enhance their usage, we reanalyze whole exome and genome sequencing data published for 684 cases of >7 common tumor types and >35 breeds, with rigorous quality control and breed validation. Our res...

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Detalles Bibliográficos
Autores principales: Alsaihati, Burair A., Ho, Kun-Lin, Watson, Joshua, Feng, Yuan, Wang, Tianfang, Dobbin, Kevin K., Zhao, Shaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333103/
https://www.ncbi.nlm.nih.gov/pubmed/34344882
http://dx.doi.org/10.1038/s41467-021-24836-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333103/
https://www.ncbi.nlm.nih.gov/pubmed/34344882
http://dx.doi.org/10.1038/s41467-021-24836-9

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