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Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds
Spontaneous canine cancers are valuable but relatively understudied and underutilized models. To enhance their usage, we reanalyze whole exome and genome sequencing data published for 684 cases of >7 common tumor types and >35 breeds, with rigorous quality control and breed validation. Our res...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333103/ https://www.ncbi.nlm.nih.gov/pubmed/34344882 http://dx.doi.org/10.1038/s41467-021-24836-9 |