High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis

We investigated whether extracellular vesicles (EVs) produced under hyperglycemic conditions could communicate signaling to drive atherosclerosis. We did so by treating Apoe(−/−) mice with exosomes produced by bone marrow-derived macrophages (BMDM) exposed to high glucose (BMDM–HG-exo) or control. I...

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Detalles Bibliográficos
Autores principales: Bouchareychas, Laura, Duong, Phat, Phu, Tuan Anh, Alsop, Eric, Meechoovet, Bessie, Reiman, Rebecca, Ng, Martin, Yamamoto, Ryo, Nakauchi, Hiromitsu, Gasper, Warren J., Van Keuren-Jensen, Kendall, Raffai, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333149/
https://www.ncbi.nlm.nih.gov/pubmed/34381972
http://dx.doi.org/10.1016/j.isci.2021.102847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333149/
https://www.ncbi.nlm.nih.gov/pubmed/34381972
http://dx.doi.org/10.1016/j.isci.2021.102847

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