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High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis
We investigated whether extracellular vesicles (EVs) produced under hyperglycemic conditions could communicate signaling to drive atherosclerosis. We did so by treating Apoe(−/−) mice with exosomes produced by bone marrow-derived macrophages (BMDM) exposed to high glucose (BMDM–HG-exo) or control. I...
Autores principales: | Bouchareychas, Laura, Duong, Phat, Phu, Tuan Anh, Alsop, Eric, Meechoovet, Bessie, Reiman, Rebecca, Ng, Martin, Yamamoto, Ryo, Nakauchi, Hiromitsu, Gasper, Warren J., Van Keuren-Jensen, Kendall, Raffai, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333149/ https://www.ncbi.nlm.nih.gov/pubmed/34381972 http://dx.doi.org/10.1016/j.isci.2021.102847 |
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