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Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila
The endoplasmic reticulum (ER)-resident transmembrane protein kinase/RNase Ire1 is a conserved sensor of the cellular unfolded protein response and has been implicated in lipid homeostasis, including lipid synthesis and transport, across species. Here we report a novel catabolic role of Ire1 in regu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333185/ https://www.ncbi.nlm.nih.gov/pubmed/34381963 http://dx.doi.org/10.1016/j.isci.2021.102819 |