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Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila

The endoplasmic reticulum (ER)-resident transmembrane protein kinase/RNase Ire1 is a conserved sensor of the cellular unfolded protein response and has been implicated in lipid homeostasis, including lipid synthesis and transport, across species. Here we report a novel catabolic role of Ire1 in regu...

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Detalles Bibliográficos
Autores principales: Zhao, Peng, Huang, Ping, Xu, Tongfu, Xiang, Xiaoxiang, Sun, Ying, Liu, Jingqi, Yan, Cheng, Wang, Lei, Gao, Jiamei, Cui, Shang, Wang, Xiangdong, Zhan, Lixing, Song, Haiyun, Liu, Jingnan, Song, Wei, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333185/
https://www.ncbi.nlm.nih.gov/pubmed/34381963
http://dx.doi.org/10.1016/j.isci.2021.102819