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Proteosomal Degradation Impairs Transcytosis of AAV vectors from Suprachoroidal Space to Retina
Suprachoroidal injection provides a new route of delivery for AAV vectors to retinal pigmented epithelial cells and photoreceptors that can be done in an outpatient setting and is less invasive and potentially safer than subretinal injection, the most common route of delivery for ocular gene therapy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333227/ https://www.ncbi.nlm.nih.gov/pubmed/33542456 http://dx.doi.org/10.1038/s41434-021-00233-1 |