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Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis

Monoamine oxidase (MAO) is believed to mediate the degradation of monoamine neurotransmitters, including dopamine, in the brain. Between the two types of MAO, MAO-B has been believed to be involved in dopamine degradation, which supports the idea that the therapeutic efficacy of MAO-B inhibitors in...

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Detalles Bibliográficos
Autores principales: Cho, Hyun-U, Kim, Sunpil, Sim, Jeongeun, Yang, Seulkee, An, Heeyoung, Nam, Min-Ho, Jang, Dong-Pyo, Lee, C. Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333267/
https://www.ncbi.nlm.nih.gov/pubmed/34244591
http://dx.doi.org/10.1038/s12276-021-00646-3