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Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
Macrophages contribute to host immunity and tissue homeostasis via alternative activation programs. M1-like macrophages control intracellular bacterial pathogens and tumor progression. In contrast, M2-like macrophages shape reparative microenvironments that can be conducive for pathogen survival or...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333345/ https://www.ncbi.nlm.nih.gov/pubmed/34381970 http://dx.doi.org/10.1016/j.isci.2021.102845 |