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Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
Macrophages contribute to host immunity and tissue homeostasis via alternative activation programs. M1-like macrophages control intracellular bacterial pathogens and tumor progression. In contrast, M2-like macrophages shape reparative microenvironments that can be conducive for pathogen survival or...
Autores principales: | Chatterjee, Sujoy, Yabaji, Shivraj M., Rukhlenko, Oleksii S., Bhattacharya, Bidisha, Waligurski, Emily, Vallavoju, Nandini, Ray, Somak, Kholodenko, Boris N., Brown, Lauren E., Beeler, Aaron B., Ivanov, Alexander R., Kobzik, Lester, Porco, John A., Kramnik, Igor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333345/ https://www.ncbi.nlm.nih.gov/pubmed/34381970 http://dx.doi.org/10.1016/j.isci.2021.102845 |
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