Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes

Interventions against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are urgently needed. Stable and potent nanobodies (Nbs) that target the receptor binding domain (RBD) of SARS-CoV-2 spike are promising therapeutics. However, it is unknown if Nbs broadly neutralize circul...

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Detalles Bibliográficos
Autores principales: Sun, Dapeng, Sang, Zhe, Kim, Yong Joon, Xiang, Yufei, Cohen, Tomer, Belford, Anna K., Huet, Alexis, Conway, James F., Sun, Ji, Taylor, Derek J., Schneidman-Duhovny, Dina, Zhang, Cheng, Huang, Wei, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333356/
https://www.ncbi.nlm.nih.gov/pubmed/34344900
http://dx.doi.org/10.1038/s41467-021-24963-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333356/
https://www.ncbi.nlm.nih.gov/pubmed/34344900
http://dx.doi.org/10.1038/s41467-021-24963-3

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