Establishment of HLA class I and MICA/B null HEK-293T panel expressing single MICA alleles to detect anti-MICA antibodies

Pre- and post-transplantation anti-MICA antibody detection development are associated with an increased rejection risk and low graft survival. We previously generated HLA class I null HEK-293T using CRISPR/Cas9, while MICA and MICB genes were removed in this study. A panel of 11 cell lines expressin...

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Detalles Bibliográficos
Autores principales: Jeon, Ji-Ho, Baek, In-Cheol, Hong, Cheol-Hwa, Park, Ki Hyun, Lee, Hyeyoung, Oh, Eun-Jee, Kim, Tai-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333366/
https://www.ncbi.nlm.nih.gov/pubmed/34344955
http://dx.doi.org/10.1038/s41598-021-95058-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333366/
https://www.ncbi.nlm.nih.gov/pubmed/34344955
http://dx.doi.org/10.1038/s41598-021-95058-8

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