Modulation of HMGB1 Release in APAP-Induced Liver Injury: A Possible Strategy of Chikusetsusaponin V Targeting NETs Formation

Acetaminophen (APAP), one of the most common antipyretic analgesics, which is safe at therapeutic dose, cause acute liver injury and even death at overdose. However, the mechanism of APAP-induced inflammation in liver injury is still controversial. Therefore, effective drug intervention is urgently...

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Detalles Bibliográficos
Autores principales: Liu, Jian, Jiang, Min, Jin, Quan, Wu, Yan-Ling, Cui, Zhen-Yu, Cui, Ben-Wen, Shang, Yue, Zhan, Zi-Ying, Lin, Yong-Ce, Jiao, Jing-Ya, Piao, Mei-Hua, Zhang, Zhi-Hong, Sun, Rong-Hui, Nan, Ji-Xing, Lian, Li-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333615/
https://www.ncbi.nlm.nih.gov/pubmed/34366873
http://dx.doi.org/10.3389/fphar.2021.723881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333615/
https://www.ncbi.nlm.nih.gov/pubmed/34366873
http://dx.doi.org/10.3389/fphar.2021.723881

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