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Neuroprotective Effect of Fisetin Through Suppression of IL-1R/TLR Axis and Apoptosis in Pentylenetetrazole-Induced Kindling in Mice

Epilepsy is a complex neurological disorder, characterized by frequent electrical activity in brain regions. Inflammation and apoptosis cascade activation are serious neurological sequelae during seizures. Fisetin (3, 3′,4′,7-tetrahydroxyflavone), a flavonoid molecule, is considered for its effectiv...

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Detalles Bibliográficos
Autores principales: Khatoon, Saima, Agarwal, Nidhi Bharal, Samim, Mohammed, Alam, Ozair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333701/
https://www.ncbi.nlm.nih.gov/pubmed/34354662
http://dx.doi.org/10.3389/fneur.2021.689069