Bicyclol Alleviates Signs of BDL-Induced Cholestasis by Regulating Bile Acids and Autophagy-Mediated HMGB1/p62/Nrf2 Pathway

Cholestasis is a liver disease characterized by the accumulation of toxic bile salts, bilirubin, and cholesterol, resulting in hepatocellular damage. Recent findings have revealed several key steps of cholestasis liver injury including the toxicity of bile acids and accumulation of proinflammatory m...

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Detalles Bibliográficos
Autores principales: Zhao, Jingwen, Ran, Maojuan, Yang, Ting, Chen, Liwei, Ji, Peixu, Xu, Xiuxiu, Zhang, Lu, Sun, Siyuan, Liu, Xin, Zhou, Simin, Zhou, Lu, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334002/
https://www.ncbi.nlm.nih.gov/pubmed/34366845
http://dx.doi.org/10.3389/fphar.2021.686502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334002/
https://www.ncbi.nlm.nih.gov/pubmed/34366845
http://dx.doi.org/10.3389/fphar.2021.686502

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