Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis

Despite recent progress in non‐small‐cell lung cancer (NSCLC) treatment, treatment outcomes remain poor, mainly because of treatment resistance or toxicity. Erastin is a ferroptosis inducer that has shown promising cytotoxic effects in various types of cancers, including NSCLC. Celastrol is a triter...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Fan, Yumei, Li, Danyu, Han, Bihui, Meng, Yanxiu, Chen, Fei, Liu, Tianchan, Song, Zhiyuan, Han, Yu, Huang, Liying, Chang, Yanzhong, Cao, Pengxiu, Nakai, Akira, Tan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334255/
https://www.ncbi.nlm.nih.gov/pubmed/33675143
http://dx.doi.org/10.1002/1878-0261.12936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334255/
https://www.ncbi.nlm.nih.gov/pubmed/33675143
http://dx.doi.org/10.1002/1878-0261.12936

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