Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage

In human, the 39 coding HOX genes and 18 referenced noncoding antisense transcripts are arranged in four genomic clusters named HOXA, B, C, and D. This highly conserved family belongs to the homeobox class of genes that encode transcription factors required for normal development. Therefore, HOX gen...

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Detalles Bibliográficos
Autores principales: Le Boiteux, Elisa, Court, Franck, Guichet, Pierre‐Olivier, Vaurs‐Barrière, Catherine, Vaillant, Isabelle, Chautard, Emmanuel, Verrelle, Pierre, Costa, Bruno M., Karayan‐Tapon, Lucie, Fogli, Anne, Arnaud, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334257/
https://www.ncbi.nlm.nih.gov/pubmed/33720519
http://dx.doi.org/10.1002/1878-0261.12944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334257/
https://www.ncbi.nlm.nih.gov/pubmed/33720519
http://dx.doi.org/10.1002/1878-0261.12944

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