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Irradiation‐induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis

Tumor repopulation occurs when residual tumor cells surviving therapies tenaciously proliferate and re‐establish the tumor. The cellular and molecular mechanisms underlying this process remain poorly understood. In this study, we propose that polyploid giant cancer cells (PGCCs) are involved in tumo...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengxiang, Feng, Xiao, Deng, Zheng, Cheng, Jin, Wang, Yiwei, Zhao, Minghui, Zhao, Yucui, He, Sijia, Huang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334289/
https://www.ncbi.nlm.nih.gov/pubmed/33523579
http://dx.doi.org/10.1002/1878-0261.12913