Pharmacologic inhibition of Akt in combination with chemotherapeutic agents effectively induces apoptosis in ovarian and endometrial cancer cell lines

The PI3K/Akt signaling pathway, the most frequently altered signaling system in human cancer, is a crucial inducer of dysregulated proliferation and neoplastic processes; however, few therapeutic strategies using PI3K/Akt inhibitors singly have been shown to be effective. The purpose of this paper w...

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Detalles Bibliográficos
Autores principales: Fabi, François, Adam, Pascal, Parent, Sophie, Tardif, Laurence, Cadrin, Monique, Asselin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334290/
https://www.ncbi.nlm.nih.gov/pubmed/33338300
http://dx.doi.org/10.1002/1878-0261.12888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334290/
https://www.ncbi.nlm.nih.gov/pubmed/33338300
http://dx.doi.org/10.1002/1878-0261.12888

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