Negative Regulation of Erythroid Differentiation via the CBX8-TRIM28 Axis

Although the mechanism of chronic myeloid leukemia (CML) initiation through BCR/ABL oncogene has been well characterized, CML cell differentiation into erythroid lineage cells remains poorly understood. Using CRISPR-Cas9 screening, we identify Chromobox 8 (CBX8) as a negative regulator of K562 cell...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Jeong, Park, Jin Woo, Kang, Joo-Young, Seo, Sang-Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334346/
https://www.ncbi.nlm.nih.gov/pubmed/34253692
http://dx.doi.org/10.14348/molcells.2021.0012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334346/
https://www.ncbi.nlm.nih.gov/pubmed/34253692
http://dx.doi.org/10.14348/molcells.2021.0012

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