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Negative Regulation of Erythroid Differentiation via the CBX8-TRIM28 Axis

Although the mechanism of chronic myeloid leukemia (CML) initiation through BCR/ABL oncogene has been well characterized, CML cell differentiation into erythroid lineage cells remains poorly understood. Using CRISPR-Cas9 screening, we identify Chromobox 8 (CBX8) as a negative regulator of K562 cell...

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Detalles Bibliográficos
Autores principales:	Kim, Hyun Jeong, Park, Jin Woo, Kang, Joo-Young, Seo, Sang-Beom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334346/ https://www.ncbi.nlm.nih.gov/pubmed/34253692 http://dx.doi.org/10.14348/molcells.2021.0012

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