Cargando…
Bispecific antibodies: A guide to model informed drug discovery and development
Affinity (KD) optimization of monoclonal antibodies is one of the factors that impacts the stoichiometric binding and the corresponding efficacy of a drug. This impacts the dose and the dosing regimen, making the optimum KD a critical component of drug discovery and development. Its importance is fu...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334385/ https://www.ncbi.nlm.nih.gov/pubmed/34381902 http://dx.doi.org/10.1016/j.heliyon.2021.e07649 |