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Single Nucleus RNA Sequence (snRNAseq) Analysis of the Spectrum of Trophoblast Lineages Generated From Human Pluripotent Stem Cells in vitro

One model to study the emergence of the human trophoblast (TB) has been the exposure of pluripotent stem cells to bone morphogenetic protein 4 (BMP4) in presence of inhibitors of ACTIVIN/TGFB; A83–01 and FGF2; PD173074 (BAP), which generates a mixture of cytotrophoblast, syncytiotrophoblast, and cel...

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Detalles Bibliográficos
Autores principales: Khan, Teka, Seetharam, Arun S., Zhou, Jie, Bivens, Nathan J., Schust, Danny J., Ezashi, Toshihiko, Tuteja, Geetu, Roberts, R. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334858/
https://www.ncbi.nlm.nih.gov/pubmed/34368143
http://dx.doi.org/10.3389/fcell.2021.695248