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Single Nucleus RNA Sequence (snRNAseq) Analysis of the Spectrum of Trophoblast Lineages Generated From Human Pluripotent Stem Cells in vitro
One model to study the emergence of the human trophoblast (TB) has been the exposure of pluripotent stem cells to bone morphogenetic protein 4 (BMP4) in presence of inhibitors of ACTIVIN/TGFB; A83–01 and FGF2; PD173074 (BAP), which generates a mixture of cytotrophoblast, syncytiotrophoblast, and cel...
Autores principales: | Khan, Teka, Seetharam, Arun S., Zhou, Jie, Bivens, Nathan J., Schust, Danny J., Ezashi, Toshihiko, Tuteja, Geetu, Roberts, R. Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334858/ https://www.ncbi.nlm.nih.gov/pubmed/34368143 http://dx.doi.org/10.3389/fcell.2021.695248 |
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