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Peptide-Based Inhibitors of ADAM and ADAMTS Metalloproteinases

ADAM and ADAMTS are two large metalloproteinase families involved in numerous physiological processes, such as shedding of cell-surface protein ectodomains and extra-cellular matrix remodelling. Aberrant expression or dysregulation of ADAMs and ADAMTSs activity has been linked to several pathologies...

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Detalles Bibliográficos
Autores principales: Pluda, Stefano, Mazzocato, Ylenia, Angelini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335159/
https://www.ncbi.nlm.nih.gov/pubmed/34368231
http://dx.doi.org/10.3389/fmolb.2021.703715