Activation of FXR Suppresses Esophageal Squamous Cell Carcinoma Through Antagonizing ERK1/2 Signaling Pathway

INTRODUCTION: Farnesoid X receptor (FXR), a member of nuclear receptors, functionally regulates bile acid, glucose and lipid homeostasis. It is also worth noting that FXR plays a suppressor role in cancer and inflammation. However, the contribution of FXR to esophageal squamous cell carcinoma (ESCC)...

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Detalles Bibliográficos
Autores principales: Feng, Qingqing, Zhang, Hongli, Yao, Denglin, Zhang, Xiantong, Chen, Wei-Dong, Wang, Yan-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335319/
https://www.ncbi.nlm.nih.gov/pubmed/34366680
http://dx.doi.org/10.2147/CMAR.S243317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335319/
https://www.ncbi.nlm.nih.gov/pubmed/34366680
http://dx.doi.org/10.2147/CMAR.S243317

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