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Improved development of mouse somatic cell nuclear transfer embryos by chlamydocin analogues, class I and IIa histone deacetylase inhibitors(†)

In mammalian cloning by somatic cell nuclear transfer (SCNT), the treatment of reconstructed embryos with histone deacetylase (HDAC) inhibitors improves efficiency. So far, most of those used for SCNT are hydroxamic acid derivatives—such as trichostatin A—characterized by their broad inhibitory spec...

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Detalles Bibliográficos
Autores principales: Kamimura, Satoshi, Inoue, Kimiko, Mizutani, Eiji, Kim, Jin-Moon, Inoue, Hiroki, Ogonuki, Narumi, Miyamoto, Kei, Ihashi, Shunya, Itami, Nobuhiko, Wakayama, Teruhiko, Ito, Akihiro, Nishino, Norikazu, Yoshida, Minoru, Ogura, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335354/
https://www.ncbi.nlm.nih.gov/pubmed/33982061
http://dx.doi.org/10.1093/biolre/ioab096