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Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9(+) T Cells

Gene editing of primary T cells is a difficult task. However, it is important for research and especially for clinical T-cell transfers. CRISPR/Cas9 is the most powerful gene-editing technique. It has to be applied to cells by either retroviral transduction or electroporation of ribonucleoprotein co...

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Detalles Bibliográficos
Autores principales:	Majumder, Snigdha, Jugovic, Isabelle, Saul, Domenica, Bell, Luisa, Hundhausen, Nadine, Seal, Rishav, Beilhack, Andreas, Rosenwald, Andreas, Mougiakakos, Dimitrios, Berberich-Siebelt, Friederike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335400/ https://www.ncbi.nlm.nih.gov/pubmed/34367143 http://dx.doi.org/10.3389/fimmu.2021.683631

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