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Statins Mitigate Stress-Related Vascular Aging and Atherosclerosis in apoE-Deficient Mice Fed High Fat-Diet: The Role of Glucagon-Like Peptide-1/Adiponectin Axis

OBJECTIVES: Exposure to chronic psychosocial stress is a risk factor for atherosclerotic cardiovascular diseases. Given that the 3-hydroxy-3-methylglutaryl-coenzyme reductase inhibitor statins prevent atherogenesis, we evaluated whether pitavastatin prevents chronic stress- and high fat diet-induced...

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Detalles Bibliográficos
Autores principales: Lei, Yanna, Cui, Qingsong, Yang, Guang, Piao, Limei, Inoue, Aiko, Wu, Hongxian, Li, Xiang, Kuzuya, Masafumi, Cheng, Xian Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335539/
https://www.ncbi.nlm.nih.gov/pubmed/34368136
http://dx.doi.org/10.3389/fcell.2021.687868