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The Fate of Two Unstoppable Trains After Arriving Destination: Replisome Disassembly During DNA Replication Termination
In eukaryotes, the perfect duplication of the chromosomes is executed by a dynamic molecular machine called the replisome. As a key step to finishing DNA replication, replisome disassembly is triggered by ubiquitylation of the MCM7 subunit of the helicase complex CMG. Afterwards, the CDC48/p97 “unfo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335557/ https://www.ncbi.nlm.nih.gov/pubmed/34368118 http://dx.doi.org/10.3389/fcell.2021.658003 |