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A reference-free approach for cell type classification with scRNA-seq

Single-cell RNA sequencing (scRNA-seq) has become a revolutionary technology to characterize cells under different biological conditions. Unlike bulk RNA-seq, gene expression from scRNA-seq is highly sparse due to limited sequencing depth per cell. This is worsened by tossing away a significant port...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Peng, Yifan, Liu, Jinze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335627/
https://www.ncbi.nlm.nih.gov/pubmed/34381979
http://dx.doi.org/10.1016/j.isci.2021.102855