Aureusidin derivative CNQX inhibits chronic colitis inflammation and mucosal barrier damage by targeting myeloid differentiation 2 protein

Our previous study has found that aureusidin can inhibit inflammation by targeting myeloid differentiation 2 (MD2) protein. Structural optimization of aureusidin gave rise to a derivative named CNQX. LPS was used to induce inflammation in intestinal macrophages; flow cytometry, PI staining and Hoech...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Sheng, Yongjia, Wang, Jin, Zhou, Xiaohong, Guan, Qiaobing, Shen, Heping, Li, Wenyan, Ruan, Shuiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335670/
https://www.ncbi.nlm.nih.gov/pubmed/34184406
http://dx.doi.org/10.1111/jcmm.16755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335670/
https://www.ncbi.nlm.nih.gov/pubmed/34184406
http://dx.doi.org/10.1111/jcmm.16755

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