HDAC6 inhibitor ACY1215 inhibits the activation of NLRP3 inflammasome in acute liver failure by regulating the ATM/F‐actin signalling pathway

Acute liver failure (ALF) is a rare and critical medical condition. This study was designed to investigate the protective effects and underlying mechanism of ACY1215 in ALF mice. Our findings suggested that ACY1215 treatment ameliorates the pathological hepatic damage of ALF and decreases the serum...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Wang, Yao, Jiao, Fangzhou, Cao, Pan, Shi, Chunxia, Pei, Maohua, Wang, Luwen, Gong, Zuojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335684/
https://www.ncbi.nlm.nih.gov/pubmed/34180140
http://dx.doi.org/10.1111/jcmm.16751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335684/
https://www.ncbi.nlm.nih.gov/pubmed/34180140
http://dx.doi.org/10.1111/jcmm.16751

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