Transcriptional activation of ENPP2 by FoxO4 protects cardiomyocytes from doxorubicin-induced toxicity

It has been shown that ferroptosis is involved in doxorubicin (DOX)-induced cardiotoxicity and that ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) can protect cardiomyocytes from ferroptosis. Thus, the present study aimed to investigate whether ENPP2 could protect cardiomyocytes from DOX...

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Detalles Bibliográficos
Autores principales: He, Ling, Yang, Yuting, Chen, Juan, Zou, Pengtao, Li, Juxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335736/
https://www.ncbi.nlm.nih.gov/pubmed/34296293
http://dx.doi.org/10.3892/mmr.2021.12307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335736/
https://www.ncbi.nlm.nih.gov/pubmed/34296293
http://dx.doi.org/10.3892/mmr.2021.12307

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