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Melatonin effect on hypoxia inducible factor-1α and clinical response in patients with oral squamous cell carcinoma receiving neoadjuvant chemotherapy: A randomized controlled trial

CONTEXT: Chemoresistance is a major issue in patients with locally advanced oral squamous cell carcinoma (OSCC). In this study, we evaluated the effectiveness of melatonin in conjunction with neoadjuvant chemotherapy (NC) on hypoxia-inducible factor-1α (HIF-1α) expression and clinical response in lo...

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Detalles Bibliográficos
Autores principales: Kartini, Diani, Taher, Akmal, Panigoro, Sonar Soni, Setiabudy, Rianto, Jusman, Sri Widia, Haryana, Sofia Mubarika, Murdani, Abdullah, Rustamadji, Primariadewi, Karisyah, Adlina, Rasyid, Sani Hadiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335757/
https://www.ncbi.nlm.nih.gov/pubmed/34429714
http://dx.doi.org/10.4103/jcar.JCar_19_20