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NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic network
Most inactivating mutations in TP53 gene generates neomorphic forms of p53 proteins that experimental evidence and clinical observations suggest to exert gain-of-function effects. While massive effort has been deployed in the dissection of wild type p53 transcriptional programme, p53 mutant pro-tumo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335924/ https://www.ncbi.nlm.nih.gov/pubmed/34348766 http://dx.doi.org/10.1186/s13062-021-00296-5 |