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NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic network

Most inactivating mutations in TP53 gene generates neomorphic forms of p53 proteins that experimental evidence and clinical observations suggest to exert gain-of-function effects. While massive effort has been deployed in the dissection of wild type p53 transcriptional programme, p53 mutant pro-tumo...

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Detalles Bibliográficos
Autores principales: Mammarella, Eleonora, Zampieri, Carlotta, Panatta, Emanuele, Melino, Gerry, Amelio, Ivano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335924/
https://www.ncbi.nlm.nih.gov/pubmed/34348766
http://dx.doi.org/10.1186/s13062-021-00296-5