Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte progenitor cell differentiation via TNFα/RelB-Hes1 pathway: a rat model study of 2,5-hexanedione-induced neurotoxicity

BACKGROUND: N-hexane, with its metabolite 2,5-hexanedine (HD), is an industrial hazardous material. Chronic hexane exposure causes segmental demyelination in the peripheral nerves, and high-dose intoxication may also affect central nervous system. Demyelinating conditions are difficult to treat and...

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Detalles Bibliográficos
Autores principales: Li, Shuangyue, Guan, Huai, Zhang, Yan, Li, Sheng, Li, Kaixin, Hu, Shuhai, Zuo, Enjun, Zhang, Cong, Zhang, Xin, Gong, Guanyu, Wang, Ruoyu, Piao, Fengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336089/
https://www.ncbi.nlm.nih.gov/pubmed/34348774
http://dx.doi.org/10.1186/s13287-021-02518-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336089/
https://www.ncbi.nlm.nih.gov/pubmed/34348774
http://dx.doi.org/10.1186/s13287-021-02518-z

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