IL-1β augments TGF-β inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics

BACKGROUND: Neutrophilic asthmatics (NA) have less response to inhaled corticosteroids. We aimed to find out the predictor of treatment response in NA. METHODS: Asthmatics (n = 115) and healthy controls (n = 28) underwent clinical assessment during 6-month follow-up with standardized therapy. Asthma...

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Detalles Bibliográficos
Autores principales: Zhang, Shengding, Fan, Yu, Qin, Lu, Fang, Xiaoyu, Zhang, Cong, Yue, Junqing, Bai, Wenxue, Wang, Gang, Chen, Zhihong, Renz, Harld, Skevaki, Chrysanthi, Liu, Xiansheng, Xie, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336269/
https://www.ncbi.nlm.nih.gov/pubmed/34344357
http://dx.doi.org/10.1186/s12931-021-01808-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336269/
https://www.ncbi.nlm.nih.gov/pubmed/34344357
http://dx.doi.org/10.1186/s12931-021-01808-7

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