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IL-1β augments TGF-β inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics

BACKGROUND: Neutrophilic asthmatics (NA) have less response to inhaled corticosteroids. We aimed to find out the predictor of treatment response in NA. METHODS: Asthmatics (n = 115) and healthy controls (n = 28) underwent clinical assessment during 6-month follow-up with standardized therapy. Asthma...

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Detalles Bibliográficos
Autores principales:	Zhang, Shengding, Fan, Yu, Qin, Lu, Fang, Xiaoyu, Zhang, Cong, Yue, Junqing, Bai, Wenxue, Wang, Gang, Chen, Zhihong, Renz, Harld, Skevaki, Chrysanthi, Liu, Xiansheng, Xie, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336269/ https://www.ncbi.nlm.nih.gov/pubmed/34344357 http://dx.doi.org/10.1186/s12931-021-01808-7

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