Genome-wide CNV investigation suggests a role for cadherin, Wnt, and p53 pathways in primary open-angle glaucoma

BACKGROUND: To investigate whether copy number variations (CNVs) are implicated in molecular mechanisms underlying primary open-angle glaucoma (POAG), we used genotype data of POAG individuals and healthy controls from two case-control studies, AGS (n = 278) and GLGS-UGLI (n = 1292). PennCNV, Quanti...

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Detalles Bibliográficos
Autores principales: Lo Faro, Valeria, ten Brink, Jacoline B., Snieder, Harold, Jansonius, Nomdo M., Bergen, Arthur A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336345/
https://www.ncbi.nlm.nih.gov/pubmed/34348663
http://dx.doi.org/10.1186/s12864-021-07846-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336345/
https://www.ncbi.nlm.nih.gov/pubmed/34348663
http://dx.doi.org/10.1186/s12864-021-07846-1

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