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Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models

BACKGROUND: Particular breast cancer subtypes pose a clinical challenge due to limited targeted therapeutic options and/or poor responses to the existing targeted therapies. While cell lines provide useful pre-clinical models, patient-derived xenografts (PDX) and organoids (PDO) provide significant...

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Detalles Bibliográficos
Autores principales: Chew, Nicole J., Lim Kam Sian, Terry C. C., Nguyen, Elizabeth V., Shin, Sung-Young, Yang, Jessica, Hui, Mun N., Deng, Niantao, McLean, Catriona A., Welm, Alana L., Lim, Elgene, Gregory, Peter, Nottle, Tim, Lang, Tali, Vereker, Melissa, Richardson, Gary, Kerr, Genevieve, Micati, Diana, Jardé, Thierry, Abud, Helen E., Lee, Rachel S., Swarbrick, Alex, Daly, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336364/
https://www.ncbi.nlm.nih.gov/pubmed/34344433
http://dx.doi.org/10.1186/s13058-021-01461-4