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Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models
BACKGROUND: Particular breast cancer subtypes pose a clinical challenge due to limited targeted therapeutic options and/or poor responses to the existing targeted therapies. While cell lines provide useful pre-clinical models, patient-derived xenografts (PDX) and organoids (PDO) provide significant...
Autores principales: | Chew, Nicole J., Lim Kam Sian, Terry C. C., Nguyen, Elizabeth V., Shin, Sung-Young, Yang, Jessica, Hui, Mun N., Deng, Niantao, McLean, Catriona A., Welm, Alana L., Lim, Elgene, Gregory, Peter, Nottle, Tim, Lang, Tali, Vereker, Melissa, Richardson, Gary, Kerr, Genevieve, Micati, Diana, Jardé, Thierry, Abud, Helen E., Lee, Rachel S., Swarbrick, Alex, Daly, Roger J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336364/ https://www.ncbi.nlm.nih.gov/pubmed/34344433 http://dx.doi.org/10.1186/s13058-021-01461-4 |
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