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Modaline sulfate promotes Oct4 expression and maintains self-renewal and pluripotency of stem cells through JAK/STAT3 and Wnt signaling pathways

BACKGROUND: Stem cells have been extensively explored for a variety of regenerative medical applications and they play an important role in clinical treatment of many diseases. However, the limited amount of stem cells and their tendency to undergo spontaneous differentiation upon extended propagati...

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Detalles Bibliográficos
Autores principales: Mei, Xianglin, Zhao, Hanhan, Ai, Huihan, Wang, Shuyue, Song, Zhenbo, Zheng, Lihua, Wang, Guannan, Sun, Ying, Bao, Yongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336387/
https://www.ncbi.nlm.nih.gov/pubmed/34348786
http://dx.doi.org/10.1186/s13578-021-00669-3